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Faculty of Arts and HumanitiesDean's Office, Faculty of Arts and HumanitiesJakobi 2, r 116-121 51005 Tartu linn, Tartu linn, Tartumaa EST0Institute of History and ArchaeologyJakobi 2 51005 Tartu linn, Tartu linn, Tartumaa EST0Institute of Estonian and General LinguisticsJakobi 2, IV korrus 51005 Tartu linn, Tartu linn, Tartumaa EST0Institute of Philosophy and SemioticsJakobi 2, III korrus, ruumid 302-337 51005 Tartu linn, Tartu linn, Tartumaa EST0Institute of Cultural ResearchÜlikooli 16 51003 Tartu linn, Tartu linn, Tartumaa EST0Institute of Foreign Languages and CulturesLossi 3 51003 Tartu linn, Tartu linn, Tartumaa EST0School of Theology and Religious StudiesÜlikooli 18 50090 Tartu linn, Tartu linn, Tartumaa EST0Viljandi Culture AcademyPosti 1 71004 Viljandi linn, Viljandimaa EST0Professors emeriti, Faculty of Arts and Humanities0Associate Professors emeriti, Faculty of Arts and Humanities0Faculty of Social SciencesDean's Office, Faculty of Social SciencesLossi 36 51003 Tartu linn, Tartu linn, Tartumaa EST0Institute of EducationJakobi 5 51005 Tartu linn, Tartu linn, Tartumaa EST0Johan Skytte Institute of Political StudiesLossi 36, ruum 301 51003 Tartu linn, Tartu linn, Tartumaa EST0School of Economics and Business AdministrationNarva mnt 18 51009 Tartu linn, Tartu linn, Tartumaa EST0Institute of PsychologyNäituse 2 50409 Tartu linn, Tartu linn, Tartumaa EST0School of LawNäituse 20 - 324 50409 Tartu linn, Tartu linn, Tartumaa EST0Institute of Social StudiesLossi 36 51003 Tartu linn, Tartu linn, Tartumaa EST0Narva CollegeRaekoja plats 2 20307 Narva linn, Ida-Virumaa EST0Pärnu CollegeRingi 35 80012 Pärnu linn, Pärnu linn, Pärnumaa EST0Professors emeriti, Faculty of Social Sciences0Associate Professors emeriti, Faculty of Social Sciences0Faculty of MedicineDean's Office, Faculty of MedicineRavila 19 50411 Tartu linn, Tartu linn, Tartumaa ESTInstitute of Biomedicine and Translational MedicineBiomeedikum, Ravila 19 50411 Tartu linn, Tartu linn, Tartumaa ESTInstitute of PharmacyNooruse 1 50411 Tartu linn, Tartu linn, Tartumaa ESTInstitute of DentistryL. Puusepa 1a 50406 Tartu linn, Tartu linn, Tartumaa ESTInstitute of Clinical MedicineL. Puusepa 8 50406 Tartu linn, Tartu linn, Tartumaa ESTInstitute of Family Medicine and Public HealthRavila 19 50411 Tartu linn, Tartu linn, Tartumaa ESTInstitute of Sport Sciences and PhysiotherapyUjula 4 51008 Tartu linn, Tartu linn, Tartumaa ESTProfessors emeriti, Faculty of Medicine0Associate Professors emeriti, Faculty of Medicine0Faculty of Science and TechnologyDean's Office, Faculty of Science and TechnologyVanemuise 46 - 208 51003 Tartu linn, Tartu linn, Tartumaa ESTInstitute of Computer ScienceNarva mnt 18 51009 Tartu linn, Tartu linn, Tartumaa ESTInstitute of GenomicsRiia 23b/2 51010 Tartu linn, Tartu linn, Tartumaa ESTEstonian Marine Institute0Institute of PhysicsInstitute of ChemistryRavila 14a 50411 Tartu linn, Tartu linn, Tartumaa EST0Institute of Mathematics and StatisticsNarva mnt 18 51009 Tartu linn, Tartu linn, Tartumaa EST0Institute of Molecular and Cell BiologyRiia 23, 23b - 134 51010 Tartu linn, Tartu linn, Tartumaa ESTTartu ObservatoryObservatooriumi 1 61602 Tõravere alevik, Nõo vald, Tartumaa EST0Institute of TechnologyNooruse 1 50411 Tartu linn, Tartu linn, Tartumaa ESTInstitute of Ecology and Earth SciencesJ. Liivi tn 2 50409 Tartu linn, Tartu linn, Tartumaa ESTProfessors emeriti, Faculty of Science and Technology0Associate Professors emeriti, Faculty of Science and Technology0Institute of BioengineeringArea of Academic SecretaryHuman Resources OfficeUppsala 6, Lossi 36 51003 Tartu linn, Tartu linn, Tartumaa EST0Area of Head of FinanceFinance Office0Area of Director of AdministrationInformation Technology Office0Administrative OfficeÜlikooli 17 (III korrus) 51005 Tartu linn, Tartu linn, Tartumaa EST0Estates Office0Marketing and Communication OfficeÜlikooli 18, ruumid 102, 104, 209, 210 50090 Tartu linn, Tartu linn, Tartumaa EST0Area of Vice Rector for DevelopmentCentre for Entrepreneurship and InnovationNarva mnt 18 51009 Tartu linn, Tartu linn, Tartumaa EST0University of Tartu Natural History Museum and Botanical GardenVanemuise 46 51003 Tartu linn, Tartu linn, Tartumaa EST0International Cooperation and Protocol Office0University of Tartu MuseumLossi 25 51003 Tartu linn, Tartu linn, Tartumaa EST0Area of RectorRector's Strategy OfficeInternal Audit OfficeArea of Vice Rector for Academic AffairsOffice of Academic AffairsUniversity of Tartu Youth AcademyUppsala 10 51003 Tartu linn, Tartu linn, Tartumaa EST0Student Union OfficeÜlikooli 18b 51005 Tartu linn, Tartu linn, Tartumaa EST0Centre for Learning and TeachingArea of Vice Rector for ResearchUniversity of Tartu LibraryW. Struve 1 50091 Tartu linn, Tartu linn, Tartumaa EST0Grant Office
Science
> LoogLab
LoogLab
Web: https://looglab.com
Contact: Group leader Prof. Mart Loog, mart.loog@ut.ee
Prof. Mart Loog’s lab focuses on understanding the processing of kinase signals via multisite phosphorylation networks in disordered proteins that control the cell cycle. Inspired by the discovered natural phosphorylation systems, we engineer multisite phosphorylation-based synthetic circuits for creative solutions and applications in synthetic biology and biotechnology.
A living cell contains thousands of molecules that mediate the cellular response to different stimuli. The networks of these molecules form a huge web of signaling circuits. Among the most important components of these circuits are protein kinases. These proteins act as molecular switches: they attach phosphoryl groups to proteins and this change mediates the transfer of signaling information.
We want to understand the phenomenon of multisite protein phosphorylation. This is a process where protein kinases add multiple phosphates to a protein and the patterns of phosphates act as complex signal processors. We look how such molecular switches regulate the cell division.
Our greater vision is to apply the discovered rules of multisite phosphorylation to engineer synthetic circuits for synthetic biology. One practical application of such “molecular toolbox” of processors and circuit elements would be to use them in designer cells that act as cell factories producing pharmaceuticals and fine chemicals via sustainable bioprocessing.
MeritsLab
Contact: Group leader Prof. Andres Merits, andres.merits@ut.ee
Each and every virus is unique and highly complex system. The complexity is hugely increased when one considers also interactions of virus with its host and, for vector transmitted viruses, with the arthropod vector. Our research focus has been RNA replication process/enzymes/complexes of positive-strand RNA viruses. As genome replication and gene expression represent the central event for infection cycle of a virus it effects directly or indirectly all other aspects of biology of viruses.
Viruses with positive-strand RNA genomes are diverse and wide-spread in nature. Many of them are major human pathogens causing millions of cases each year: coronaviruses, dengue virus (DENV), noroviruses, rhinoviruses to name just few. Others have known to cause sudden outbreaks and epidemics; recent examples include Zika virus (ZIKV, family Flaviviridae, genus Flavivirus) outbreak 2015-2016 and chikungunya virus (CHIKV, family Togaviridae, genus Alphavirus) outbreaks 2005-2008 and 2013.
Viruses causing epidemics use different modes of transmission. These include droplet/aerosol transmission (SARS-CoV-2) and transmission by arthropod vectors (ZIKV, CHIKV). Our research group has been engaged in basic and applied studies of alphaviruses that are pathogenic for humans: CHIKV, Ross River virus (RRV), Barmah Forest virus (BFV), o’nyong’nyong virus (ONNV), Eastern equine encephalitis virus (EEEV), Sindbis virus (SINV) and also Semliki Forest virus (SFV), not associated with known diseases. During outbreak of ZIKV our research interest was extended to flaviviruses and, by obvious reasons, at 2020 extended again 2020 to include SARS-CoV-2. We maintain research competence with those viruses.
KollistLab
Web: https://www.plantsignalresearch.com
Contact: Group leader Prof. Hannes Kollist, Hannes.Kollist@ut.ee
Hannes Kollist Lab aims to study mechanisms by which plants sense changes in the environment. As a tool for our research we use Arabidopsis mutants and mutant screens. Furthermore natural variation among Arabidopsis exotypes is used as a source of genetic information and the long standing aim is to transfer knowledge collected from the model species to crops and trees. The research carried out in the lab can be divided into three interconnected topics: Guard cell signaling, Stomatal regulation of crops, Biochemistry of organelles.
GasFermTec Lab
Contact: Group leader Prof. Kaspar Valgepea, kaspar.valgepea@ut.ee
GasFermTec group research focuses on advancing gas fermentation technologies through its The Valgepea Lab led by Dr. Kaspar Valgepea focuses on the integration of gas fermentation technologies with systems and synthetic biology to address global challenges of biosustainability by developing bioprocesses that would realise sustainable production of fuels and chemicals. We employ acetogen bacteria to recycle carbon from inexpensive and abundant waste feedstocks (e.g. waste gases, gasified biomass) into value-added products. We investigate fundamentals of acetogen metabolism, develop novel systems and synthetic biology tools, and apply metabolic engineering for the creation of acetogen cell factories. We are an international team of researchers and students collaborating globally with both academia and industry. Recently, group leader Kaspar Valgepea received the ERC Consolidator grant for next-generation engineering of gas-fermenting cell factories through large-scale systems-level phenotype maps.